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Vaccination against Mycoplasma has demonstrated positive economic returns. Two-dose bacterins have consistently reduced the economic impact of Mycoplasma infection on Average Daily Gain (ADG), Feed Conversion Ratio (FCR) and Medicatioan Cost. Less often, reduction in cough and mortality are seen. Farms with continuous production are most severely affected, and provide the greatest opportunity for profitable vaccination.

In more than ten large scale field studies with Ingelvac^® M.hyo similar results have been garnered. Improved ADG and FC, along with reduced culls & mortality, are consistent returns from vaccination. For example, improvement in ADG of 25 to 30 gm/day (0.04 to 0.05 #/day) is seen. Studies ranged from 20 to over 200 batches of pigs. Larger numbers of groups were studied to be certain the performance of vaccine was detectable, or “statistically significant”.

When compared to conventional two-dose vaccines in side by side trials, Ingelvac^® M.hyo has met or exceeded the performance of conventional vaccines (p<0.05). Several two-dose products are available, with similar results noted clinically and economically. In nine field studies, involving over 160,000 pigs, performance was equal to conventional vaccines for FC and Cull/Mortality in every study! Ingelvac^® M.hyo beat other vaccines in ADG by an average of 3.2%! Results in ADG ranged from a “Tie” to 6.3% better ADG than conventional vaccine. Demonstrated one dose protection meeting, or beating, market expectations in any challenge!

Summary of Ingelvac^® M.hyo performance vs. non-vaccinated pigs
(7 studies; 367,860 vaccinated pigs)

Economic Parameter	Min.	Max.	Ave. Perfor.
ADG	+3.2%	+5.9%	+4.7%
FCR	-1.0%	-9.2%	-3.2%
Mortality	-23%	-35%	-29.5%

Application

Timing vaccination

Vaccinate pigs for Mycoplasma four weeks ahead of exposure, or 5-6 weeks prior to cough. This allows pigs to develop immunity prior to exposure, but minimizes the potential interaction of maternal immunity. Use serology or cough scoring to determine when the time of exposure is occurring.

More information

Meas, et al. Effect of vaccination against Mycoplasma hyopneumoniae in pig herds with an all in-all out production system. Vaccine 17 (1999) 1024-1034.

Thacker E, Thacker B. Vaccination as a means of controlling Mycoplasma hyopneumoniae. Proceedings Allen D. Leman Conference. 2000; 84-86.